If you've been thinking about taking a GLP-1 (Glucagon Like Peptides 1) medication to lose weight, you may be wondering what the differences of compounded vs brand name GLP-1s are.
Many of my clients are asking me about GLP-1 providers like Ro and Remedy Meds (you may have heard of them). But during their research, their finding out about compounded semaglutide, compounded tirzepatide and brand name meds like Ozempic®, Wegovy®, Zepbound®, and more.
As a health coach with a fairly large community, I have to stay on top of all this information. I still recommend a healthy diet and a strength training program. However, I can't turn a blind eye to GLP-1 medications because so many people are interested in it.
So what's the differences in compounded vs brand-name GLP-1 medications? This article will go over exactly what you need to know. It serves as a resource that I send to my clients.
What Are Brand-Name GLP-1 Medications?
Brand-name GLP-1 medications like Ozempic®, Wegovy®, and Zepbound® are FDA-approved drugs that contain semaglutide or tirzepatide. They are manufactured by pharmaceutical companies such as Novo Nordisk and Eli Lilly and have undergone rigorous clinical trials to prove their safety and effectiveness.
Pros of Brand-Name GLP-1s:
- FDA-approved for weight loss (Wegovy®, Zepbound®) or type 2 diabetes (Ozempic®, Mounjaro®, prescribed off-label for weight loss)
- Consistent dosage and formulation
- Prescribed by a doctor and typically covered by insurance (if you qualify)
- Extensively tested in clinical trials
Cons of Brand-Name GLP-1s:
- Often expensive without insurance coverage
- Limited availability due to high demand
- Requires a prescription from a healthcare provider
What Are Compounded GLP-1 Medications?
Compounded GLP-1 medications are customized formulations made by compounding pharmacies. They contain the same active ingredients as brand-name medications (semaglutide or tirzepatide) but are mixed by pharmacists to meet demand, especially when the brand-name versions are in short supply.
Pros of Compounded GLP-1s:
- More affordable than brand-name versions
- Often available when brand-name meds are on shortage
- Can be tailored to specific patient needs
- Offered by telehealth services like Remedy Meds
Cons of Compounded GLP-1s:
- Not FDA-approved (though made in highly regulated pharmacies)
- May vary in formulation and quality between pharmacies
- Insurance typically does not cover compounded versions
How Do You Choose Between Compounded and Brand-Name GLP-1s?
If you have insurance and qualify, a brand-name GLP-1 medication may be the best choice because of its proven effectiveness and FDA approval. However, if brand-name medications are out of stock, not covered by your insurance, or too expensive, compounded versions can be a viable alternative.
GLP-1 Providers That Offer Compounded GLP-1s
What Remedy Meds Offers
Remedy Meds is a telehealth platform that provides access to compounded semaglutide and tirzepatide through U.S.-licensed doctors and pharmacies. Their program includes:
- A 2-minute questionnaire to determine eligibility
- Monthly check-ins with a licensed provider
- Direct-to-door delivery of medication
- Transparent pricing without hidden fees
See my detailed review of RemedyMeds to learn more
Perimenopause, Menopause, Midlife Women (Compounded GLP-1s)
Many of my clients in perimenopause and menopause struggle with weight loss due to hormonal changes. While diet and strength training are always my first recommendations, some find that adding a GLP-1 medication helps them break through plateaus.
I’ve found that compounded GLP-1s through providers like Join Josie are a more accessible option for many midlife women. They don’t require insurance, and the process is straightforward, with online access to doctors and medication delivered to your door.
For women navigating menopause, managing weight can feel even more frustrating due to changing metabolism and body composition. That’s why I’ve also put together a guide on the best menopause GLP-1 providers for those who want a solution specifically tailored to midlife weight loss.
If you do decide it's the right option for you, check out our success tips for menopause and GLP-1s, which should help you get the most out of your use.
Final Thoughts
Both brand-name and compounded GLP-1s have their place in weight loss treatment. If you're considering a GLP-1 medication, it's important to weigh the pros and cons based on availability, cost, and personal health needs. Remedy Meds offers a straightforward and affordable option for those who may not have access to brand-name medications.
If you’re looking for more information on GLP-1 medications or need help choosing the right provider, feel free to reach out—I’m here to help guide you through the process.